In a large sample of privately insured children who had older siblings with autism spectrum disorder (ASD) and thus were at higher risk of developing autism, receipt of the MMR vaccine was not associated with increased risk of ASD, regardless of whether older siblings had ASD. The findings indicate no harmful association between MMR vaccine receipt and ASD even among children already at higher risk for ASD. The project was funded by the National Institute of Mental Health, National Institutes of Health, and the US Department of Health and Human Services under contract HHSN-271-2010-00033-C.

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Cite this as JAMA. 2015;313(15):1534-1540