E mail from CDC to CNN, Breakthrough infections
https://www.medscape.com/viewarticle/949381?src=wnl_edit_tpal&uac=127834AR&impID=3316056&faf=1
https://edition.cnn.com/2021/04/14/health/breakthrough-infections-covid-vaccines-cdc/index.html
Vaccinated people who become infected = 5,800
About 1 in 13,275
At least 14 days after their final dose
Asymptomatic, 29%
Required hospitalization = 396 (1 in 194,444)
Deaths = 74 (1 in 1,040,540)
CDC currently investigating factors
May be more cases to report due to reporting lag
From 77 million fully vaccinated
(Fully vaccinated as of today = 80.6 million)
From trials
Pfizer/BioNTech, 95% effective in preventing symptomatic disease
Moderna, 94% effective in preventing symptomatic illness
Johnson & Johnson, 72% from US data
Characteristics of breakthroughs so far
40% of the infections were in people 60 or more
65%, were female
CDC is monitoring reported cases for clustering by patient demographics, geographic location, time since vaccination, vaccine type or lot number, and SARS-CoV-2 lineage
CDC also continues to recommend people who have been fully vaccinated should keep taking precautions in public places, like wearing a mask, staying at least six feet apart from others, avoiding crowds and poorly ventilated spaces, and washing their hands often
Dr. Carlos del Rio, Emory University School of Medicine
Less transmission means fewer breakthrough cases
There is currently a lot of transmission in many parts of the country
Vaccines will help decrease that
Get vaccinated as soon as you can and help control this pandemic
National Institutes of Health Director Dr Francis Collins
Allow more time for scientists to investigate links between the vaccine and blood clots
and whether or not certain groups of people are more susceptible
India, double mutation variant emerge
Hey john thanks for the update. I am from Delhi, India and I have contracted the virus. Situation in India is very bad. Most of the hospitals are already exhausted and many people are dying without treatment.
The India variant, B.1.617
E484Q and L452R
First reported in India, late 2020
Aparna Mukherjee, Indian Council of Medical Research
has not been stamped as a ‘variant of concern’ so as to say that it is more lethal or more infectious
But
https://www.healio.com/news/infectious-disease/resources/outbreak-tracker
Very low prevalence in January
April, 52% of samples sequenced
Maharashtra state, 60%
Has been detected in 10 other countries, US, UK (77 cases) Australia and New Zealand
(L452 from US data, 20% more transmissible, reduces antibody efficacy by more 50%)
William A. Haseltine, former professor, Harvard Medical School
The B.1.617 variant has all the hallmarks of a very dangerous virus
We must do all that is possible to identify its spread and to contain it
Brazil
https://www.washingtonpost.com/nation/2021/04/16/coronavirus-covid-live-updates-us/
Trying to get more drugs from Spain
Rio de Janeiro, health-care workers forced to intubate patients without sedatives
Mechanical restraints and neuromuscular blockers
Doctors Without Borders
More than 12 months into Brazil’s covid-19 emergency, there is still no effective, centralized and coordinated public health response to the outbreak
The lack of political will to adequately respond to the pandemic is killing Brazilians in their thousands